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Posted by / 22-Dec-2020 12:33

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Less frequently encountered findings include cleft lip and palate, preauricular tags and fistulas, thymic dysplasia, intestinal malrotation, megacolon, inguinal hernia, dislocated hips, cryptorchidism, hypospadias, rare renal malformations (e.g., horseshoe kidneys, renal ectopia or agenesis, hydronephrosis), clinodactyly of the fifth fingers, talipes equinovarus, pes planus, syndactyly of the second and third fingers and toes, oligosyndactyly and hyper extensible joints.The syndrome may also include various dermatoglyphics, including transverse flexion creases, distal axial triradius, increased whorls and arches on digits and a single palmar crease.

Affected females reach puberty, develop secondary sex characteristics and menstruate at the usual time.Two genes in these regions, Semaphorine F (SEMA5A) and delta catenin (CTNND2), are potentially involved in cerebral development.The deletion of the telomerase reverse transcriptase (h TERT) gene localized in 5p15.33 may contribute to the phenotypic changes in cri du chat syndrome as well.He has threatened legal action against the artist and HAU, accusing both of entrapment.The artist maintains the project stoked a necessary debate on privacy and identity online.

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Other symptoms of cri du chat syndrome may include: Other common findings include hypotonia, a round face with full cheeks, epicanthal folds, down-slanting palpebral fissures (eyelids), strabismus, flat nasal bridge, down-turned mouth, low-set ears, short fingers, single palmar creases and cardiac defects (e.g., ventricular septal defect [VSD], atrial septal defect [ASD], patent ductus arteriosus [PDA], tetralogy of Fallot). It has also been observed that people with the condition have difficulties communicating.

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